Navigating the Unknown: How International Lynch Syndrome Awareness Day, 22 March, Serves as a Guiding Constellation for Romania
Lynch syndrome, formerly known as Hereditary Non-Polyposis Colorectal Cancer (HNPCC), characterized by a defective DNA mismatch repair, is the most common autosomal dominant hereditary predisposition to several malignancies. LS patients typically exhibit an elevated risk of developing multiple primary malignancies with early onset.